Panathinaikos could not avoid defeat at Piraeus, and now they are getting in trouble. Panathinaikos lost 81-78. Once again, they had significant problems in defense, while in the attack, they shoot at 1/20, an amateur level percentage.

Things are too complicated. Pitino emphasized that his players must now play like Spartans, but nothing can be done only with heart and willing unless this is combined with good methodical basketball.

Panathinaikos have made three defeats in a row and five in their last six games. In 12 of his last 13 games, they have received more than 80 points per game from its opponents.

Nikos Pappas is out by Pitino's decision. There is no other injury concern for Panathinaikos.

CSKA looked shocked by the defeat at home to Barcelona and entered the match with Zenit in a slow mood. They might have underestimated their opponent, so they struggled throughout the game. They eventually won with 86-78.

James scored 27 points, losing just five shots and having 100% in free throws. CSKA knows that if they want to be in the top-4, they should win this game.

In the last five games, they have had three defeats, both of which came home, with the same score (80-82). Except for Olympiacos' loss, they have scored at least 80 points in its last four games.

Andrey Vorontsevich is the only absence for CSKA Moscow due to injury. Will Clyburn is a long-term injury matter.

The overall record in Euroleague since 2000, is Panathinaikos - CSKA Moscow 16-18.

In the first round, Panathinaikos beat CSKA Moscow 106-102 in overtime.

Let's take a look at main and special odds markets offered at bet365 website :

• FullTime Result: 1.68(Panathinaikos) - 2.25(CSKA Moscow)
• Over/Under 169.5 points: 1.90 (Over) - 1.90 (Under)
• Race to 20 points: 1.76(Panathinaikos) - 1.90(CSKA Moscow)

*bet365 odds as offered at  10/10, 15:00CET (subject to change without prior notice) | 18+, T&Cs Apply, BeGambleAware.org

 Nick Calathes and Mike James will have to face each other. Ex-teammates, the one knows the other' way.

It will be a crucial matchup that may decide the final winner of the game.